Fasil Tekola Ayele, Ph.D.

Fasil Tekola Ayele

Fasil Tekola-Ayele, M.P.H., Ph.D., is a Research Fellow at the Center for Research on Genomics and Global Health (CRGGH), National Human Genome Research Institute (NHGRI), National Institutes of Health (NIH). His research focuses on genetics and epidemiology of podoconiosis, type 2 diabetes/metabolic syndrome, and population genetics. Since 2004, he has done a body of research on podoconiosis and has published on the clinical-epidemiology, economic and social burden, bioethical issues surrounding genetic research, genetic-epidemiology, adaptive genetic selection, and translation of genetics research on podoconiosis to public health. His lead-authored research published in the New England Journal of Medicine in 2012 has led to the discovery of genetic variants that confer susceptibility to podoconiosis. He has published the first genome-wide association study on plasma levels of three interleukins in African-Americans. He is co-lead author of an international collaborative research namely the African Genome Variation Project that has provided new insights into the genetic variation landscape of several African populations published in Nature in 2014. His overall research interest is on genetic and environmental basis of common diseases and its public health translation, with a long term goal of contributing to the betterment of global health. Dr. Tekola-Ayele is a recipient of the 2014 Intramural Research Award from the NHGRI/NIH.

Dr. Tekola-Ayele received his B.Sc. in Public Health from Debub University; M.P.H. from Addis Ababa University, Ethiopia; and Ph.D. in Genetic Epidemiology from Brighton and Sussex Medical School, Universities of Brighton and Sussex, UK. He worked as a clinician and a community health coordinator in a health center followed by research assistant and lecturer position in Addis Ababa University. He coordinated and led the implementation, analysis, write-up and dissemination of the first Nationwide HIV/AIDS Health Facility Survey in Ethiopia. Following his Ph.D., he worked as a Research Manager in the Mossy Foot Treatment and Prevention Association, Ethiopia and as a post-doctoral fellow at the CRGGH/NHGRI/NIH.